Renovos is developing promising regenerative medicine technologies using unique synthetic nanoclay gels. These nanoclay gels can be used for bone repair and tissue regeneration.
Nanoclay Platform Technology
Stem cells can cure a variety of conditions by regenerating tissue. They are activated by powerful biochemical molecules from within their local microenvironment. Localising and retaining these bioactive molecules close to a healing site is key to the safety and efficacy of all regenerative medicine applications. However, conventional biomaterials are often poor at retaining these molecules at the site of injury, and the molecules that stimulate the cells diffuse away.
For decades clays have been used in tablets to control drug release through their molecule binding properties. For instance, these binding properties ensure that molecules stay localised, which is essential to directing the activity of stem cells.
Renovos has developed an innovative solution to molecule diffusion based on synthetic nanoclay gels. These injectable nanoclay gels provide a localised environment conductive to cell attachment and infiltration, acting as a scaffold. They can also localise and retain molecules, which can be used at much lower doses. Cells infiltrating the nanoclay gels get exposed to these molecules which direct their activity, and the nanoclay scaffold is gradually replaced with newly regenerated tissue.
Our nanoclay platform ensures localised concentration and release of biologics, drugs and cells, enhancing safety and efficacy of these agents for regenerative medicine.
About Renovos’ proprietary Nanoclay technologies:
Safety of biologics – reduced ectopic and/or non-specific effects
Efficacy of biologics – sustained localised concentrations and preserved bioactivity
Cost reduction – reduced doses by an order of magnitude through improved localisation and efficacy
Ease of use – clay particle self-assembly allows for minimally invasive, injectable delivery and in-situ gelation
Customisable – allowing for co-delivery of agents and spatial complexity through simple mixing procedures
30-year history of use in cosmetics and toothpaste formulations
Collaborate with us:
Our nanoclay formulations are suitable for many applications. Therefore, Renovos welcomes enquiries from potential partners with an interest in one of Renovos’ in-house development programmes or wishing to utilise our technologies in their own R&D.
Please get in touch to discuss your requirements. Contact us >